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osteoblast
Osteoblast
Mesenchymal-derived bone-forming cells that synthesise type I collagen matrix and initiate mineralisation via alkaline phosphatase-rich matrix vesicles. Master regulator Runx2 integrates BMP, Wnt, and PTH signals; RANKL/OPG ratio couples osteoblasts to osteoclast activity.
Entry Metadata
| Field | Value |
|---|---|
| ID | osteoblast |
| Name | Osteoblast |
| Status | draft |
| Last reviewed | 2026-06-05 |
| Atlas | 01-human |
| Scale | 04-cellular |