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gambling-disorder
Gambling Disorder
Gambling disorder (0.5-3% prevalence) is the prototypical behavioral addiction: dopamine reward dysregulation, near-miss effect, D2/D3R hypofunction, and loss-chasing. Opioid antagonists (naltrexone) have the best pharmacological evidence; CBT and peer support are first-line.
Entry Metadata
| Field | Value |
|---|---|
| ID | gambling-disorder |
| Name | Gambling Disorder |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Grant JE, Chamberlain SR. Gambling disorder and its relationship with substance use disorders: implications for nosological revisions and treatment. Am J Addict. 2015;24(2):126-131. · PubMed 25376793
- Potenza MN. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond B Biol Sci. 2008;363(1507):3181-3189. · PubMed 18640909
- Grant JE, Kim SW, Hollander E, Potenza MN. Predicting response to opiate antagonists and placebo in the treatment of pathological gambling. Psychopharmacology (Berl). 2008;200(4):521-527. · PubMed 18668226