Atlas One · Host Biology · Scale 07 — System

COPD

Chronic obstructive pulmonary disease from cigarette smoke-induced alveolar destruction (emphysema) and airway remodeling; FEV1/FVC <0.7 defines obstruction. Bronchodilators (LABA/LAMA) are first-line; inhaled corticosteroids reduce exacerbations in eosinophilic COPD.

Also known as: chronic obstructive pulmonary disease, emphysema, chronic bronchitis, COPD-asthma overlap, ACO

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
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copd

COPD

Chronic obstructive pulmonary disease from cigarette smoke-induced alveolar destruction (emphysema) and airway remodeling; FEV1/FVC <0.7 defines obstruction. Bronchodilators (LABA/LAMA) are first-line; inhaled corticosteroids reduce exacerbations in eosinophilic COPD.

Entry Metadata

FieldValue
IDcopd
NameCOPD
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

targetsRespiratory System connects-toTgf Beta connects-toMacrophage connects-toNeutrophil connects-toLung connects-toAsthma connects-toIl 1B connects-toCystic Fibrosis connects-toHeart connects-toStreptococcus Pneumoniae connects-toNsclc connects-toRsv connects-toCarbon

Sources