Atlas One · Host Biology · Scale 07 — System

Influenza

Influenza A/B (orthomyxovirus; segmented negative-sense RNA) causes seasonal epidemics (H1N1, H3N2) and pandemics (1918 H1N1 killed ~50M; H5N1 mortality 60%); NS1 evades RIG-I/MAVS/STAT1; oseltamivir inhibits neuraminidase; baloxavir targets PA; annual vaccines 40-60% effective.

Also known as: influenza, flu, influenza A, influenza B, H1N1, H3N2, H5N1, avian influenza, seasonal flu, pandemic influenza, orthomyxovirus, hemagglutinin, neuraminidase, oseltamivir, Tamiflu, baloxavir

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
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influenza

Influenza

Influenza A/B (orthomyxovirus; segmented negative-sense RNA) causes seasonal epidemics (H1N1, H3N2) and pandemics (1918 H1N1 killed ~50M; H5N1 mortality 60%); NS1 evades RIG-I/MAVS/STAT1; oseltamivir inhibits neuraminidase; baloxavir targets PA; annual vaccines 40-60% effective.

Entry Metadata

FieldValue
IDinfluenza
NameInfluenza
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toMavs connects-toType I Interferon connects-toStat1 connects-toNlrp3 Inflammasome

Sources