Atlas One · Host Biology · Scale 03 — Molecular

Influenza Hemagglutinin

Influenza hemagglutinin (HA; homotrimer) binds sialic acid on airway epithelium (α2,6-SA human; α2,3-SA avian) and drives pH-triggered membrane fusion; HA1 head antigenic sites A-E drive annual drift; HA2 stalk is conserved and broadly targeted for universal influenza vaccines.

Also known as: hemagglutinin, HA, influenza HA, HA1, HA2, HA stalk, HA head, influenza surface glycoprotein, H1N1 hemagglutinin, H3N2 hemagglutinin, H5 hemagglutinin, HA antigenic sites

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
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influenza-ha

Influenza Hemagglutinin

Influenza hemagglutinin (HA; homotrimer) binds sialic acid on airway epithelium (α2,6-SA human; α2,3-SA avian) and drives pH-triggered membrane fusion; HA1 head antigenic sites A-E drive annual drift; HA2 stalk is conserved and broadly targeted for universal influenza vaccines.

Entry Metadata

FieldValue
IDinfluenza-ha
NameInfluenza Hemagglutinin
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toInfluenza connects-toRsv F Protein connects-toSars Cov 2 Spike connects-toSurfactant analogue-ofMv H Protein connects-toType Ii Pneumocyte

Sources