Atlas One · Host Biology · Scale 03 — Molecular

RSV F Protein

RSV fusion (F) protein (class I viral fusogen; 574 aa; pre-F and post-F conformations) mediates RSV-host membrane fusion → syncytia; prefusion site Ø is the dominant neutralizing epitope targeted by nirsevimab and mRNA vaccines; DS-Cav1 proline locks F in prefusion for vaccines.

Also known as: RSV F protein, RSV fusion protein, prefusion F, post-fusion F, site Ø, DS-Cav1, nirsevimab target, RSV F glycoprotein, RSVpreF, respiratory syncytial virus fusion glycoprotein

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
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rsv-f-protein

RSV F Protein

RSV fusion (F) protein (class I viral fusogen; 574 aa; pre-F and post-F conformations) mediates RSV-host membrane fusion → syncytia; prefusion site Ø is the dominant neutralizing epitope targeted by nirsevimab and mRNA vaccines; DS-Cav1 proline locks F in prefusion for vaccines.