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rsv
RSV
RSV (pneumovirus; negative-sense ssRNA) is the leading cause of infant bronchiolitis and severe LRTI in elderly/immunocompromised; NS1/NS2 block MAVS/IFN-β; nirsevimab (anti-F mAb) prevents severe infant RSV; mRNA-1345 (Abrysvo) and mResvia approved 2023 for adults 60+.
Entry Metadata
| Field | Value |
|---|---|
| ID | rsv |
| Name | RSV |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Shi T, McAllister DA, O'Brien KL, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet. 2017;390(10098):946-958. · PubMed 28689664
- Hammitt LL, Dagan R, Yuan Y, et al. Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants. N Engl J Med. 2022;386(9):837-846. · PubMed 35196424