MV-H Protein
Measles hemagglutinin (H; type II transmembrane; 617 aa) binds SLAM/CD150 on immune cells and nectin-4 on airway epithelium; SLAM tropism explains immune amnesia; H-F fusion complex drives syncytia; N-glycan shield on H is a barrier to vaccine-elicited neutralizing antibodies.
Entry Metadata
| Field | Value |
|---|---|
| ID | mv-h-protein |
| Name | MV-H Protein |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 03-molecular |
Cross-Atlas Connections
Sources
- Tatsuo H, Ono N, Tanaka K, Yanagi Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature. 2000;406(6798):893-897. · PubMed 10972291
- Mühlebach MD, Mateo M, Sinn PL, et al. Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Nature. 2011;480(7378):530-533. · PubMed 22048310