Atlas Two · Pathogen Atlas · 02-bacteria

Clostridioides difficile

Gram-positive anaerobic spore-forming rod; reclassified from Clostridium in 2016. Causes antibiotic-associated colitis via TcdA/TcdB glucosyltransferase toxins and binary toxin (CDT). NAP1/027 hypervirulent ribotype; FMT ~90% effective for recurrent CDI.

Also known as: C. difficile, C. diff, Clostridium difficile, CDI, CDAD, NAP1/027 strain

02-bacteriaClass
draftStatus
2026-06-05Last Reviewed
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clostridioides-difficile

Clostridioides difficile

Gram-positive anaerobic spore-forming rod; reclassified from Clostridium in 2016. Causes antibiotic-associated colitis via TcdA/TcdB glucosyltransferase toxins and binary toxin (CDT). NAP1/027 hypervirulent ribotype; FMT ~90% effective for recurrent CDI.

Entry Metadata

FieldValue
IDclostridioides-difficile
NameClostridioides difficile
Statusdraft
Last reviewed2026-06-05
Class02-bacteria

Cross-Atlas Connections

infectsIntestinal Epithelium damagesDigestive System damagesImmune System damagesNeutrophil connects-toOmeprazole treated-byVancomycin connects-toAmoxicillin modulated-byLactobacillus Rhamnosus

Sources