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peyers-patches
Peyer's Patches
Unencapsulated lymphoid nodules in ileal submucosa; primary inductive site of gut mucosal immunity. M cells in follicle-associated epithelium sample luminal antigens; germinal centers produce IgA-committed B cells that migrate to lamina propria for secretory IgA synthesis.
Entry Metadata
| Field | Value |
|---|---|
| ID | peyers-patches |
| Name | Peyer's Patches |
| Status | draft |
| Last reviewed | 2026-06-06 |
| Atlas | 01-human |
| Scale | 05-tissue |
Cross-Atlas Connections
Sources
- Cornes JS. Number, size, and distribution of Peyer's patches in the human small intestine. Gut. 1965;6(3):225-233. · PubMed 5826791
- Neutra MR, Frey A, Kraehenbuhl JP. Epithelial M cells: gateways for mucosal infection and immunization. Cell. 1996;86(3):345-348. · PubMed 8756715
- Fagarasan S, Honjo T. Intestinal IgA synthesis: regulation of front-line body defences. Nat Rev Immunol. 2003;3(1):63-72. · PubMed 12511876