Mission
Model the human body as one coherent system — across every scale.
Model human biology end-to-end: from quarks and electrons up to molecules, cells, tissues, organs, systems, and whole-body physiology. Make that model precise enough that we can engineer, reverse-engineer, and re-engineer biology with the same rigor we apply to silicon and software.
The end goal: when the next fast-mutating pathogen appears, a candidate vaccine is hours away — not months or years. And eventually, an adaptive immune layer that generalizes to threats we haven't seen yet.
Atlas One · Host Biology
The same system, viewed at every magnification.
Biology at one level constrains and explains the next. The model has to be coherent across all of them — physics under chemistry, chemistry under cells, cells under organs, organs under us.
Subatomic
Quarks, electrons, photons — the substrate of all chemistry. Photon · Proton · Electron
Atomic
Elements and bonds that make biology physically possible. Hydrogen · Carbon · Nitrogen · Oxygen · Sodium · Potassium · Calcium · Magnesium · Iron · Phosphorus · Sulfur · Chloride · Copper · Zinc · Selenium · Iodine
Molecular
Proteins, nucleic acids, lipids — the working parts of cells. Serotonin · IL-6 · Cortisol · Insulin · TNF-α · ATP · GR · NF-κB · Insulin R · STAT3 · SERT · Cx43 · HCN4 · NCX1 · PLN · RyR2 · SERCA2a · Troponin · Albumin · Collagen · IgG · MHC II · EPO · Fibrinogen · Cholesterol · Hemoglobin · Leptin · Glucagon · Vasopressin · Prostaglandins · Nitric Oxide · Thyroid Hormones · AMPK · Dopamine · Norepinephrine · Epinephrine · Acetylcholine · GABA · Glutamate · Histamine · Complement C3 · Platelet · Angiotensin II · β1-AR
Cellular
The smallest unit that's unambiguously alive. Macrophage · Erythrocyte · NK Cell · Cardiomyocyte · SA Node Cell · T Helper · CD8+ T Cell · B Cell · Dendritic Cell · Neutrophil · Mast Cell · Plasma Cell · T Reg · Osteoblast · Osteoclast · Type II Pneumocyte · Hepatocyte · Endothelial Cell · Smooth Muscle · Fibroblast · Adipocyte · Neuron · Astrocyte · Microglia · Oligodendrocyte · Podocyte
Tissue
Cells specialized and organized into functional fabrics. Bone Marrow · Intestinal Epithelium · Myocardium · Endocardium · Conduction System · Cortical Bone · Alveolus · Glomerulus · Hepatic Lobule · Arterial Wall · Synapse · Islet of Langerhans
Organ
Tissues coordinated into a single functional unit. Heart · Brain · Kidney · Liver · Lung · Pancreas · Spleen · Thymus · Adrenal Gland · Thyroid · Stomach · Small Intestine · Large Intestine · Hippocampus
System
Immune, nervous, circulatory, endocrine — networks of organs. Cardiovascular · Nervous · Immune · Respiratory · Digestive · Renal · Endocrine · Musculoskeletal · Lymphatic · Integumentary · Reproductive
Whole Body
An integrated organism — the unit we actually live in.
Atlas Two · Pathogens & Microbes
Every threat. Every microbe. Modeled the same way.
A vaccine is a designed interface between a host and a pathogen. To build that interface in hours, both sides need to be modeled at the same depth.
The Pathogen Atlas catalogs every microbe and pathogen that touches human biology — its structure, mechanism of harm, immune signature, and mutation pressure. The same scale ladder, viewed from the other side of the encounter.
Viruses
Influenza, coronaviruses, HIV, herpes, ebola — fast mutation, highest-priority threat class. HIV-1 · Hepatitis B · Influenza A · SARS-CoV-2 · Dengue · HCV · HPV-16
Bacteria
TB, staph, strep, mycobacteria — antibiotic resistance and cell-cell warfare with the immune system. S. pneumoniae · M. tuberculosis · S. aureus · E. coli · C. tetani
Fungi
Candida, aspergillus, cryptococcus — emerging threats with few drug classes. C. albicans · A. fumigatus
Parasites
Plasmodium, helminths, trypanosomes — global disease burden, complex life cycles. P. falciparum
Microbiome
Gut, skin, respiratory commensals — not every microbe is a threat; many are partners. L. rhamnosus GG
Together with the Medicine and Vaccine Atlases, the four open atlases form a training corpus for AI agents working on the next vaccine — and an educational foundation for human researchers, clinicians, and students, in every part of the world.
Atlas Three · The Medicine Atlas
An encyclopedia of every medicine humanity has used to heal.
The third atlas catalogs the interface between host and pathogen — every drug, vaccine, herb, food, and traditional therapy. Modern pharmaceuticals and 3,000-year-old healing systems held to the same standard: what it is, how it works, where the evidence stands.
Modern
Pharmaceuticals, biologics, vaccines, gene therapy — the science of the last two centuries.
Traditional & Cultural
Ayurveda, Chinese medicine, indigenous traditions — millennia of refined healing knowledge.
Food & Nutrition
Spices, fermented foods, dietary patterns — the medicines we already eat.
Atlas Four · The Vaccine Atlas
Every vaccine humanity has built, by platform.
The fourth atlas catalogs prophylactic vaccines — organized by delivery platform. Each entry covers antigen design, mechanism of immunity, clinical efficacy, safety profile, cold-chain requirements, and connections to the Human and Pathogen atlases.
mRNA
Lipid-nanoparticle mRNA encoding spike or other antigen. Fastest to design, highest immunogenicity. mRNA-1273 · BNT162b2
Viral Vector
Replication-incompetent adenovirus delivering antigen gene. Single dose feasible; VITT risk. AZD1222 · Ervebo
Recombinant Subunit
Purified protein + adjuvant. Longest safety track record; no nucleic acid. NVX-CoV2373
Inactivated
Whole-virion killed vaccine. Refrigerator-stable; broad antigen coverage; alum adjuvant. CoronaVac · Rabies Vaccine
Live-Attenuated
Replication-competent attenuated organism. Strongest cellular immunity; trained innate immunity. BCG · Rotarix
Toxoid
Formalin-inactivated bacterial toxins. Durable humoral immunity; aluminium adjuvant. Tetanus Toxoid
VLP
Recombinant virus-like particles — no nucleic acid, dense multivalent antigen display. Gardasil-9
Capabilities
What the model unlocks.
If we have coherent multi-scale models of both atlases — and the AI to reason over them — four capabilities become tractable.
Engineer
Design new biology — proteins, cells, tissues, immune responses — from first principles, with predictable behavior.
Reverse-engineer
Take a pathogen, disease, or healthy mechanism and recover its mechanism end-to-end.
Re-engineer
Repair, optimize, or replace components of human biology with the confidence of a hardware swap.
Immunize
Design adaptive defenses that generalize across fast-mutating threats — not chase each variant in retrospect.
Why now
Three thresholds crossed at once.
For most of history, a project this ambitious would have been science fiction. In the last decade, three different fields each crossed a threshold — and they did it at roughly the same time.
The cost of slowness is now legible.
COVID-19 measured the gap between pathogen and vaccine in millions of lives. Next time, that gap should be hours.
Compute and AI are ready.
Protein folding, molecular dynamics, multi-scale simulation, and foundation models for biology have all crossed feasibility thresholds.
Biology is increasingly engineerable.
CRISPR, mRNA platforms, synthetic biology, and high-throughput assays make biology behave more like a programmable system every year.
Join the effort
Anyone. Anywhere. Any contribution.
This is a project for humanity, by humanity. No matter your discipline, your country, or your stage of career — there is a way to contribute. The model needs every kind of mind.
Support the work
Donations fund freedom — for everyone.
The model, the data, and the tools will always be free. Donations pay for the compute, the researchers, and the infrastructure that keeps it that way. Every contribution — small or large — moves the timeline forward.
Funding channels — opening soon
We're setting up transparent, accountable channels for donations (open finances, public ledger). In the meantime: star the repo, share the mission, and reach out if you'd like to fund early work directly.