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all
Acute Lymphoblastic Leukemia
ALL is a lymphoid progenitor malignancy; B-ALL ~85% (ETV6-RUNX1 t(12;21) ~25% pediatric; BCR-ABL1 Ph+ ~25% adult; Ph-like ~15%); T-ALL ~15% (NOTCH1 ~60%); overall pediatric 5-year OS >90%; adult OS ~40-50%.
Entry Metadata
| Field | Value |
|---|---|
| ID | all |
| Name | Acute Lymphoblastic Leukemia |
| Status | draft |
| Last reviewed | 2026-06-06 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Pui CH, Yang JJ, Bhakta N, et al. Global efforts toward the cure of childhood acute lymphoblastic leukemia. Lancet Child Adolesc Health. 2018;2(6):440-454. · PubMed 29976322
- Maude SL, Laetsch TW, Buechner J, et al. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia. N Engl J Med. 2018;378(5):439-448. · PubMed 29385370