Atlas One · Host Biology · Scale 07 — System

Acute Lymphoblastic Leukemia

ALL is a lymphoid progenitor malignancy; B-ALL ~85% (ETV6-RUNX1 t(12;21) ~25% pediatric; BCR-ABL1 Ph+ ~25% adult; Ph-like ~15%); T-ALL ~15% (NOTCH1 ~60%); overall pediatric 5-year OS >90%; adult OS ~40-50%.

Also known as: ALL, acute lymphoblastic leukemia, acute lymphocytic leukemia, B-ALL, T-ALL, Ph+ ALL, Ph-like ALL, pediatric leukemia, ETV6-RUNX1 ALL, BCR-ABL1 ALL

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
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all

Acute Lymphoblastic Leukemia

ALL is a lymphoid progenitor malignancy; B-ALL ~85% (ETV6-RUNX1 t(12;21) ~25% pediatric; BCR-ABL1 Ph+ ~25% adult; Ph-like ~15%); T-ALL ~15% (NOTCH1 ~60%); overall pediatric 5-year OS >90%; adult OS ~40-50%.