Atlas One · Host Biology · Scale 07 — System

Acute Lymphoblastic Leukemia

ALL is a lymphoid progenitor malignancy; B-ALL ~85% (ETV6-RUNX1 t(12;21) ~25% pediatric; BCR-ABL1 Ph+ ~25% adult; Ph-like ~15%); T-ALL ~15% (NOTCH1 ~60%); overall pediatric 5-year OS >90%; adult OS ~40-50%.

Also known as: ALL, acute lymphoblastic leukemia, acute lymphocytic leukemia, B-ALL, T-ALL, Ph+ ALL, Ph-like ALL, pediatric leukemia, ETV6-RUNX1 ALL, BCR-ABL1 ALL

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
all

Acute Lymphoblastic Leukemia

ALL is a lymphoid progenitor malignancy; B-ALL ~85% (ETV6-RUNX1 t(12;21) ~25% pediatric; BCR-ABL1 Ph+ ~25% adult; Ph-like ~15%); T-ALL ~15% (NOTCH1 ~60%); overall pediatric 5-year OS >90%; adult OS ~40-50%.

Entry Metadata

FieldValue
IDall
NameAcute Lymphoblastic Leukemia
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toRunx1 connects-toNotch connects-toBcl 2 connects-toPd 1 connects-toB Cell connects-toAbl1 connects-toT Helper Cell connects-toAplastic Anemia connects-toBone Marrow connects-toAml connects-toCml connects-toBurkitt Lymphoma connects-toThymus connects-toT Cytotoxic Cell connects-toPhoton connects-toDlbcl connects-toPlatelet connects-toBrain connects-toSpleen connects-toCd20 connects-toErythrocyte connects-toPcnsl connects-toNeutrophil connects-toLi Fraumeni Syndrome connects-toImmune System connects-toKidney connects-toReproductive System connects-toNatural Killer Cell connects-toGlucocorticoid Receptor connects-toCalcium connects-toLiver connects-toHeart connects-toRegulatory T Cell connects-toPotassium connects-toPhosphorus connects-toEye connects-toMyc connects-toElectron connects-toSkin connects-toMagnesium connects-toNeuron connects-toAntibody connects-toPancreas connects-toMusculoskeletal System connects-toHepatocyte connects-toAdrenal Gland connects-toGvhd connects-toMtor connects-toMacrophage connects-toNervous System connects-toPneumocystis Jirovecii connects-toNf Kb connects-toStat3 connects-toSepsis connects-toVenous Thromboembolism connects-toAspergillus Fumigatus connects-toOsteoporosis connects-toHeart Failure connects-toNeuropathic Pain connects-toCkd connects-toMajor Depressive Disorder connects-toEndocrine System connects-toDigestive System connects-toVaricella Zoster Virus connects-toLymphatic System connects-toRenal System connects-toIntegumentary System connects-toCardiovascular System connects-toRespiratory System connects-toHerpesvirus connects-toCancer Chemotherapy connects-toCar T connects-toTargeted Therapy connects-toCortical Bone connects-toHippocampus connects-toCll connects-toMds connects-toIntestinal Epithelium connects-toHodgkin Lymphoma connects-toCar T connects-toCytokine Storm connects-toGlomerulus connects-toP53 connects-toEpstein Barr Virus connects-toCovid 19 Disease connects-toJak1 2 connects-toCdk4 6 connects-toEzh2 connects-toCdkn2A connects-toCxcl12 connects-toAkt connects-toMen1 connects-toFlt3 connects-toCaspase 3 connects-toPerforin connects-toIgf 1 connects-toFoxo connects-toPik3Ca connects-toErk1 2 connects-toE2F1 connects-toPten connects-toKras connects-toWnt Beta Catenin connects-toTgf Beta connects-toGalectin 3 connects-toHif 1Alpha connects-toStat1 connects-toCgas Sting connects-toSmad4 connects-toGsk 3B connects-toS100A8 A9 connects-toMdm2 connects-toSrc Kinase connects-toDnmt3A connects-toAutophagy connects-toAmpk connects-toCcr5 connects-toArid1A connects-toIl 1B connects-toIl 33 connects-toIl 6 connects-toIl 17A connects-toComplement C3 connects-toCalcineurin connects-toXanthine Oxidase connects-toMhc Class Ii connects-toIl 2 connects-toHemoglobin connects-toTroponin Complex connects-toProton connects-toIl 10 connects-toIron connects-toVegf connects-toIl 4 connects-toAdiponectin connects-toLeptin connects-toCalcium connects-toIl 13 connects-toResistin connects-toCml connects-toBurkitt Lymphoma connects-toIron connects-toIfn Gamma connects-toIl 12 connects-toType I Interferon connects-toIl 5 connects-toIl 23 connects-toIge connects-toDendritic Cell connects-toPlasma Cell connects-toC5Ar1 connects-toComplement C5 connects-toFactor H connects-toTransferrin connects-toTslp connects-toBradykinin connects-toErythropoietin connects-toHistamine connects-toMelatonin connects-toC1 Esterase Inhibitor connects-toTestosterone connects-toSerotonin connects-toProlactin connects-toOxytocin connects-toVasopressin connects-toSelenium connects-toSodium connects-toZinc connects-toCopper connects-toIodine connects-toChloride connects-toSulfur connects-toCarbon connects-toHydrogen connects-toNitrogen connects-toOxygen connects-toGlp 1 connects-toAngiotensin Ii connects-toRankl connects-toFibronectin connects-toActivin A connects-toCgrp connects-toCalcitonin connects-toSubstance P connects-toInsulin Receptor connects-toAldosterone connects-toAndrogen Receptor connects-toNorepinephrine connects-toAdrenomedullin connects-toBdnf connects-toOsteopontin connects-toFgfr connects-toEpinephrine

Sources