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men1-syndrome
MEN1 Syndrome
Multiple Endocrine Neoplasia type 1 (MEN1) is caused by germline MEN1 mutations; triad of parathyroid adenomas (>95%), pituitary adenomas (20-65%), and pancreatic NETs (30-80%); everolimus FDA-approved for pNETs; annual biochemical + MRI surveillance.
Entry Metadata
| Field | Value |
|---|---|
| ID | men1-syndrome |
| Name | MEN1 Syndrome |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Thakker RV, Newey PJ, Walls GV, et al. Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1). J Clin Endocrinol Metab. 2012;97(9):2990-3011. · PubMed 22392070
- Chandrasekharappa SC, Guru SC, Manickam P, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science. 1997;276(5311):404-407. · PubMed 9103196