Atlas One · Host Biology · Scale 07 — System

Carney Complex

Carney complex is caused by germline PRKAR1A mutations; spotty skin pigmentation, cardiac myxomas, primary pigmented nodular adrenocortical disease (PPNAD) causing Cushing syndrome, pituitary GH adenomas, and Sertoli cell tumors; annual cardiac MRI surveillance.

Also known as: Carney complex, PRKAR1A syndrome, CNC, Carney PPNAD, Carney cardiac myxoma, Carney Cushing, PPNAD hereditary, Carney lentiginosis, Carney complex PRKAR1A

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
carney-complex

Carney Complex

Carney complex is caused by germline PRKAR1A mutations; spotty skin pigmentation, cardiac myxomas, primary pigmented nodular adrenocortical disease (PPNAD) causing Cushing syndrome, pituitary GH adenomas, and Sertoli cell tumors; annual cardiac MRI surveillance.

Entry Metadata

FieldValue
IDcarney-complex
NameCarney Complex
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toPrkar1A connects-toCortisol connects-toNeuroendocrine Tumors connects-toPheochromocytoma Paraganglioma connects-toHeart connects-toAdrenal Gland connects-toIgf 1 connects-toEndocrine System connects-toSkin connects-toMen1 Syndrome connects-toThyroid Cancer connects-toSchwannomatosis connects-toGrowth Hormone connects-toCardiomyocyte connects-toMen4 Syndrome connects-toReproductive System connects-toThyroid connects-toFibroblast connects-toProlactin connects-toIntegumentary System connects-toCardiovascular System connects-toNervous System connects-toBreast Cancer connects-toBrain connects-toEstrogen connects-toActh connects-toCollagen connects-toCalcium connects-toPeripheral Nerve connects-toWnt Beta Catenin connects-toMtor connects-toEye connects-toPotassium connects-toEndothelial Cell connects-toPhoton connects-toOsteoblast connects-toTestosterone connects-toElectron connects-toLung connects-toBone Marrow connects-toNeuron connects-toErythrocyte connects-toPlatelet connects-toStroke connects-toOsteoclast connects-toAkt connects-toIl 6 connects-toPeutz Jeghers Syndrome connects-toAdipocyte connects-toHeart Failure connects-toOvarian Cancer connects-toTuberous Sclerosis Complex connects-toNf Kb connects-toMelanoma connects-toVenous Thromboembolism connects-toOsteoporosis connects-toType 2 Diabetes connects-toMajor Depressive Disorder connects-toHypertension connects-toWound Healing connects-toSepsis connects-toMusculoskeletal System connects-toObesity connects-toGeneralized Anxiety Disorder connects-toImmune System connects-toRespiratory System connects-toDigestive System connects-toNoonan Syndrome connects-toStaphylococcus Aureus connects-toLi Fraumeni Syndrome connects-toVhl Disease connects-toNeurofibromatosis Type 2 connects-toCowden Syndrome connects-toEndocardium connects-toCortical Bone connects-toNeurofibromatosis Type 1 connects-toArterial Wall connects-toBirt Hogg Dube Syndrome connects-toMyocardium connects-toGist connects-toDicer1 Syndrome connects-toGorlin Syndrome connects-toCardiac Conduction System connects-toCyclin D1 connects-toErk1 2 connects-toMyc connects-toVegf connects-toHif 1Alpha connects-toThyroid Hormones connects-toKit connects-toActivin A connects-toGsk 3B connects-toFoxo1 connects-toTgf Beta connects-toGlucocorticoid Receptor connects-toAndrogen Receptor connects-toCalcium connects-toCdk4 6 connects-toPik3Ca connects-toE2F1 connects-toSmad4 connects-toBcl 2 connects-toNotch connects-toPten connects-toGalectin 3 connects-toStat3 connects-toStat1 connects-toCgas Sting connects-toEzh2 connects-toPerforin connects-toS100A8 A9 connects-toMdm2 connects-toSrc Kinase connects-toDnmt3A connects-toAutophagy connects-toAmpk connects-toCcr5 connects-toArid1A connects-toCxcl12 connects-toIl 1B connects-toIl 33 connects-toIl 17A connects-toComplement C3 connects-toCalcineurin connects-toAtp connects-toEndothelin 1 connects-toTroponin Complex connects-toPdgf connects-toFgfr connects-toNitric Oxide connects-toAldosterone connects-toInsulin connects-toXanthine Oxidase connects-toBrain connects-toThyroid connects-toSchwannomatosis connects-toCholesterol connects-toIl 4 connects-toLeptin connects-toAdrenal Gland connects-toThyroid connects-toIl 13 connects-toAdiponectin connects-toResistin connects-toIfn Gamma connects-toIl 12 connects-toIl 5 connects-toIl 23 connects-toT Cytotoxic Cell connects-toT Helper Cell connects-toMast Cell connects-toMacrophage connects-toComplement C5 connects-toC5Ar1 connects-toTslp connects-toBradykinin connects-toErythropoietin connects-toHistamine connects-toMelatonin connects-toC1 Esterase Inhibitor connects-toSerotonin connects-toOxytocin connects-toVasopressin connects-toSelenium connects-toIodine connects-toSodium connects-toCopper connects-toIron connects-toMagnesium connects-toZinc connects-toPhosphorus connects-toChloride connects-toCarbon connects-toHydrogen connects-toNitrogen connects-toPd 1 connects-toGlp 1 connects-toAngiotensin Ii connects-toRankl connects-toIl 2 connects-toFibronectin connects-toCgrp connects-toCalcitonin connects-toSubstance P connects-toInsulin Receptor connects-toNorepinephrine connects-toAdrenomedullin connects-toBdnf connects-toOsteopontin connects-toEpinephrine connects-toRenin connects-toMyostatin connects-toAngiopoietin

Sources