Atlas One · Host Biology · Scale 07 — System

Neurofibromatosis Type 2

Neurofibromatosis type 2 (NF2) is caused by germline NF2 mutations; bilateral vestibular schwannomas are pathognomonic; meningiomas, ependymomas also occur; merlin activates Hippo-YAP1; bevacizumab improves hearing; TEAD inhibitors in clinical trials.

Also known as: NF2, neurofibromatosis type 2, NF2 syndrome, bilateral acoustic neuroma, NF2 vestibular schwannoma, NF2 merlin, NF2 bevacizumab, neurofibromatosis 2, acoustic neuroma hereditary

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
neurofibromatosis-type-2

Neurofibromatosis Type 2

Neurofibromatosis type 2 (NF2) is caused by germline NF2 mutations; bilateral vestibular schwannomas are pathognomonic; meningiomas, ependymomas also occur; merlin activates Hippo-YAP1; bevacizumab improves hearing; TEAD inhibitors in clinical trials.

Entry Metadata

FieldValue
IDneurofibromatosis-type-2
NameNeurofibromatosis Type 2
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toNf2 connects-toYap1 connects-toMeningioma connects-toMesothelioma connects-toVegf connects-toSchwannomatosis connects-toPeripheral Nerve connects-toNeurofibromatosis Type 1 connects-toBrain connects-toRenal Cell Carcinoma

Sources