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neuroblastoma
Neuroblastoma
Neuroblastoma is the most common extracranial pediatric solid tumor; neural crest-derived; MYCN amplification in ~40% high-risk; tandem auto-SCT + dinutuximab (anti-GD2) + 13-cis-retinoic acid maintenance for high-risk; ALK inhibitors in Phase 3 trials.
Entry Metadata
| Field | Value |
|---|---|
| ID | neuroblastoma |
| Name | Neuroblastoma |
| Status | draft |
| Last reviewed | 2026-06-06 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Yu AL, Gilman AL, Ozkaynak MF, et al. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med. 2010;363(14):1324-1334. · PubMed 20879881
- Park JR, Kreissman SG, London WB, et al. Effect of tandem autologous stem cell transplant vs single transplant on event-free survival in patients with high-risk neuroblastoma: a randomized clinical trial. JAMA. 2019;322(8):746-755. · PubMed 31454023