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ewing-sarcoma
Ewing Sarcoma
Ewing sarcoma is an EWSR1-ETS fusion-driven small round blue cell tumor of bone/soft tissue; peak age 10-20 years; EWSR1-FLI1 ~85%; localized 5-year EFS ~60-70%; metastatic ~15-25%; VCD/IE or VIDE induction; local control by surgery ± RT; HDCT+auto-SCT for high-risk.
Entry Metadata
| Field | Value |
|---|---|
| ID | ewing-sarcoma |
| Name | Ewing Sarcoma |
| Status | draft |
| Last reviewed | 2026-06-06 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Grier HE, Krailo MD, Tarbell NJ, et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med. 2003;348(8):694-701. · PubMed 12594313
- Ladenstein R, Potschger U, Le Deley MC, et al. Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial. J Clin Oncol. 2010;28(20):3284-3291. · PubMed 20498398