Atlas One · Host Biology · Scale 07 — System

Wilms Tumor

Wilms tumor (nephroblastoma) is the most common pediatric renal malignancy; peak age 3-4 years; favorable histology ~90% with 4-year OS >95%; anaplastic ~10% with TP53 mutations; WT1/CTNNB1/WTX/DROSHA drivers; actinomycin D+vincristine±doxorubicin backbone.

Also known as: Wilms tumor, nephroblastoma, Wilms' tumor, pediatric kidney cancer, childhood renal tumor, nephroblastoma WAGR, Wilms anaplastic

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
wilms-tumor

Wilms Tumor

Wilms tumor (nephroblastoma) is the most common pediatric renal malignancy; peak age 3-4 years; favorable histology ~90% with 4-year OS >95%; anaplastic ~10% with TP53 mutations; WT1/CTNNB1/WTX/DROSHA drivers; actinomycin D+vincristine±doxorubicin backbone.

Entry Metadata

FieldValue
IDwilms-tumor
NameWilms Tumor
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toWt1 connects-toWnt Beta Catenin connects-toP53 connects-toMtor connects-toKidney connects-toPodocyte connects-toIgf 1 connects-toRhabdomyosarcoma connects-toNeuroblastoma connects-toLi Fraumeni Syndrome

Sources