Atlas One · Host Biology · Scale 07 — System

Esophageal Cancer

Esophageal cancer includes ESCC (squamous, smoking/alcohol) and EAC (adenocarcinoma, Barrett's/HER2+ ~15%); nivolumab+chemotherapy (CheckMate 648) is first-line for ESCC; trastuzumab+chemotherapy (ToGA) and T-DXd for HER2+ EAC; 5-year OS ~20%.

Also known as: esophageal cancer, ESCC, esophageal squamous cell carcinoma, EAC, esophageal adenocarcinoma, Barrett's esophagus cancer, GEJ cancer, gastroesophageal junction cancer, CheckMate 648, ATTRACTION-3

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
esophageal-cancer

Esophageal Cancer

Esophageal cancer includes ESCC (squamous, smoking/alcohol) and EAC (adenocarcinoma, Barrett's/HER2+ ~15%); nivolumab+chemotherapy (CheckMate 648) is first-line for ESCC; trastuzumab+chemotherapy (ToGA) and T-DXd for HER2+ EAC; 5-year OS ~20%.

Entry Metadata

FieldValue
IDesophageal-cancer
NameEsophageal Cancer
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toNfe2L2 connects-toPd 1 connects-toHer2 connects-toVegf connects-toEgfr connects-toFgfr connects-toGastric Cancer connects-toHnscc connects-toStomach connects-toT Cytotoxic Cell connects-toObesity connects-toAlcohol Use Disorder connects-toCarbon

Sources