Atlas One · Host Biology · Scale 07 — System

Werner Syndrome

Werner syndrome is caused by biallelic WRN mutations; premature aging onset in 3rd decade — cataracts, scleroderma-like skin, gray hair, type 2 diabetes, dyslipidemia, osteoporosis, atherosclerosis; cancer risk elevated (sarcomas, melanoma, thyroid); median survival ~47-54 years.

Also known as: Werner syndrome, Werner's syndrome, Werner progeroid syndrome, WRN syndrome, adult progeria, Werner syndrome WRN, premature aging Werner, Werner syndrome cancer, RECQL2 Werner syndrome

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
werner-syndrome

Werner Syndrome

Werner syndrome is caused by biallelic WRN mutations; premature aging onset in 3rd decade — cataracts, scleroderma-like skin, gray hair, type 2 diabetes, dyslipidemia, osteoporosis, atherosclerosis; cancer risk elevated (sarcomas, melanoma, thyroid); median survival ~47-54 years.

Entry Metadata

FieldValue
IDwerner-syndrome
NameWerner Syndrome
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toWrn connects-toTert connects-toType 2 Diabetes connects-toOsteoporosis connects-toFibroblast connects-toEye connects-toAtherosclerosis connects-toBloom Syndrome connects-toOsteosarcoma connects-toThyroid Cancer

Sources