Atlas One · Host Biology · Scale 07 — System

Bloom Syndrome

Bloom syndrome is caused by biallelic BLM mutations; small body size, sun-sensitive telangiectatic facial erythema, immunodeficiency; elevated sister chromatid exchanges (~10x); pan-cancer predisposition (ALL, lymphoma, GI carcinoma, skin cancers); median survival ~30 years.

Also known as: Bloom syndrome, Bloom's syndrome, BLM syndrome, Bloom syndrome cancer, Bloom syndrome SCE, RECQL3 syndrome, Bloom syndrome ALL, Bloom syndrome chromosomal instability, Bloom syndrome hereditary

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
bloom-syndrome

Bloom Syndrome

Bloom syndrome is caused by biallelic BLM mutations; small body size, sun-sensitive telangiectatic facial erythema, immunodeficiency; elevated sister chromatid exchanges (~10x); pan-cancer predisposition (ALL, lymphoma, GI carcinoma, skin cancers); median survival ~30 years.

Entry Metadata

FieldValue
IDbloom-syndrome
NameBloom Syndrome
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toBlm connects-toBrca1 connects-toWrn connects-toColorectal Cancer connects-toBurkitt Lymphoma connects-toApc connects-toMlh1 connects-toDicer1 Syndrome connects-toSkin connects-toAll connects-toWerner Syndrome connects-toAml connects-toPhoton

Sources