Atlas One · Host Biology · Scale 07 — System

Cervical Cancer

Cervical cancer is HPV-driven in >99% of cases; HPV E6/E7 oncoproteins degrade p53 and inactivate RB → immortalization. Cisplatin + chemoradiation is standard for locally advanced; pembrolizumab + chemotherapy (KEYNOTE-826) is approved for PD-L1+ recurrent/metastatic disease.

Also known as: cervical cancer, cervical carcinoma, HPV cervical cancer, squamous cell carcinoma cervix, cervical adenocarcinoma, FIGO cervical cancer, invasive cervical cancer

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
cervical-cancer

Cervical Cancer

Cervical cancer is HPV-driven in >99% of cases; HPV E6/E7 oncoproteins degrade p53 and inactivate RB → immortalization. Cisplatin + chemoradiation is standard for locally advanced; pembrolizumab + chemotherapy (KEYNOTE-826) is approved for PD-L1+ recurrent/metastatic disease.

Entry Metadata

FieldValue
IDcervical-cancer
NameCervical Cancer
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toPd 1 connects-toRb1 connects-toP53 connects-toVegf connects-toHpv 16 connects-toPik3Ca connects-toKras connects-toHnscc connects-toHiv Aids connects-toT Cytotoxic Cell connects-toBladder Cancer connects-toEndometrial Cancer connects-toOvarian Cancer

Sources