Atlas One · Host Biology · Scale 07 — System

Ovarian Clear Cell Carcinoma

Ovarian clear cell carcinoma (OCCC) is an endometriosis-derived subtype; ARID1A (~50%) and PIK3CA (~50%) are hallmark mutations; platinum-resistant; no FDA-approved targeted therapy; higher incidence in Asian women; mTOR inhibitors and EZH2 inhibitors under investigation.

Also known as: OCCC, ovarian clear cell carcinoma, clear cell ovarian cancer, endometriosis-associated ovarian cancer, ARID1A ovarian cancer, PIK3CA ovarian clear cell, clear cell adenocarcinoma ovary, endometrioid-related ovarian cancer, ovarian cancer clear cell, CCC ovarian

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
ovarian-clear-cell-carcinoma

Ovarian Clear Cell Carcinoma

Ovarian clear cell carcinoma (OCCC) is an endometriosis-derived subtype; ARID1A (~50%) and PIK3CA (~50%) are hallmark mutations; platinum-resistant; no FDA-approved targeted therapy; higher incidence in Asian women; mTOR inhibitors and EZH2 inhibitors under investigation.

Entry Metadata

FieldValue
IDovarian-clear-cell-carcinoma
NameOvarian Clear Cell Carcinoma
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toArid1A connects-toEzh2 connects-toPik3Ca connects-toPd 1 connects-toMtor connects-toKras connects-toOvarian Cancer connects-toEndometrial Cancer connects-toRenal Cell Carcinoma connects-toT Cytotoxic Cell connects-toVenous Thromboembolism connects-toLynch Syndrome connects-toReproductive System connects-toGastric Cancer connects-toCholangiocarcinoma connects-toHereditary Breast Ovarian Cancer connects-toPten connects-toNatural Killer Cell connects-toVhl Disease connects-toP53 connects-toImmune System connects-toHif 1Alpha connects-toCalcium connects-toIl 6 connects-toFibroblast connects-toIron connects-toVegf connects-toMacrophage connects-toOxygen connects-toLarge Intestine connects-toDendritic Cell connects-toKidney connects-toEndothelial Cell connects-toFibrosis connects-toElectron connects-toPlatelet connects-toLiver connects-toNeuron connects-toAlbumin connects-toLung connects-toAntibody connects-toNeutrophil connects-toMagnesium connects-toNfe2L2 connects-toAkt connects-toT Helper Cell connects-toEstrogen connects-toMet connects-toRegulatory T Cell connects-toStat3 connects-toNf Kb connects-toSepsis connects-toCyclin D1 connects-toCkd connects-toAnemia Of Chronic Disease connects-toOsteoporosis connects-toMajor Depressive Disorder connects-toHeart Failure connects-toNeuropathic Pain connects-toWound Healing connects-toGeneralized Anxiety Disorder connects-toEndocrine System connects-toRespiratory System connects-toDigestive System connects-toLymphatic System connects-toCardiovascular System connects-toNervous System connects-toRenal System connects-toTargeted Therapy connects-toMusculoskeletal System connects-toBladder Cancer connects-toCancer Chemotherapy connects-toCheckpoint Inhibitors connects-toGerminal Center connects-toHcc connects-toColorectal Cancer connects-toIntestinal Epithelium connects-toHlrcc connects-toAlveolus connects-toDisseminated Intravascular Coagulation connects-toArterial Wall connects-toMesothelioma connects-toYap1 connects-toNotch connects-toTert connects-toMyc connects-toCdk4 6 connects-toTgf Beta connects-toCcl2 connects-toIl 1B connects-toCgas Sting connects-toCaspase 3 connects-toPth connects-toThrombin connects-toBcl 2 connects-toMlh1 connects-toEpas1 connects-toE2F1 connects-toErk1 2 connects-toCdh1 connects-toJak1 2 connects-toMyd88 connects-toRb1 connects-toGalectin 3 connects-toSmad4 connects-toPdgf connects-toStat1 connects-toFoxo connects-toCdkn2A connects-toGsk 3B connects-toMdm2 connects-toS100A8 A9 connects-toSrc Kinase connects-toDnmt3A connects-toAutophagy connects-toAmpk connects-toCcr5 connects-toPerforin connects-toCxcl12 connects-toIl 33 connects-toIl 17A connects-toAxl Receptor connects-toMhc Class Ii connects-toProgesterone connects-toIl 2 connects-toCtla 4 connects-toTroponin Complex connects-toHemoglobin connects-toIl 10 connects-toXanthine Oxidase connects-toProstaglandins connects-toIl 4 connects-toNitric Oxide connects-toIl 13 connects-toIron connects-toLeptin connects-toAdiponectin connects-toResistin connects-toHepcidin connects-toType I Interferon connects-toIfn Gamma connects-toIl 12 connects-toIl 5 connects-toIl 23 connects-toIge connects-toMast Cell connects-toComplement C5 connects-toC5Ar1 connects-toTransferrin connects-toFactor H connects-toB Cell connects-toErythropoietin connects-toBradykinin connects-toC1 Esterase Inhibitor connects-toTslp connects-toHistamine connects-toPeriostin connects-toMelatonin connects-toTestosterone connects-toSerotonin connects-toProlactin connects-toOxytocin connects-toVasopressin connects-toSelenium connects-toIodine connects-toSodium connects-toCopper connects-toPotassium connects-toPhosphorus connects-toCarbon connects-toChloride connects-toHydrogen connects-toNitrogen connects-toSulfur connects-toAngiotensin Ii connects-toGlp 1 connects-toWnt Beta Catenin connects-toRankl connects-toFibronectin connects-toIgf 1 connects-toActivin A connects-toCgrp connects-toCalcitonin connects-toSubstance P connects-toInsulin Receptor connects-toAldosterone connects-toAndrogen Receptor connects-toNorepinephrine connects-toAdrenomedullin connects-toBdnf connects-toOsteopontin connects-toFgfr connects-toEpinephrine

Sources